双歧杆菌在5-氟尿嘧啶作用下的适应性变化
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刘俊康, 邓 渝, 吴小兰, 魏海龙, 徐启旺
双歧杆菌;化疗药物;5-氟尿嘧啶;生物波;原子力显微镜刘俊康,邓渝,吴小兰,魏海龙,徐启旺.双歧杆菌在5-氟尿嘧啶作用下的适应性变化. 世界华人消化杂志2006;14(32)3139-31
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刘俊康, 邓渝, 吴小兰, 魏海龙, 徐启旺, 第三军医大学医学检验系生物波研究室 重庆市 400038重庆市科委自然科学基金计划资助项目, No. CSTC2006BB5068
通讯作者: 徐启旺, 400038, 重庆市沙坪坝区高滩岩正街30号, 第三军医大学医学检验系生物波研究室. tmmubc@163.com
电话: 023-68752191
收稿日期: 2006-07-28 接受日期: 2006-08-22
Adaptive changes of bifidobacteria in the presence of 5-fluorouracil
Jun-Kang Liu, Yu Deng, Xiao-Lan Wu, Hai-Long Wei, Qi-Wang Xu
Jun-Kang Liu, Yu Deng, Xiao-Lan Wu, Hai-Long Wei, Qi-Wang Xu, Research Center of Bio-wave, Department of Laboratory Medicine, the Third Military Medical University, Chongqing 400038, China
Supported by the Natural Science Planning Foundation of Chongqing Science and Technology Commitee, No. CSTC2006BB5068
Correspondence to: Qi-Wang Xu, Research Center of Bio-wave, the Third Military Medical University, Chongqing 400038, China. tmmubc@163.com
Received: 2006-07-28 Accepted: 2006-08-22
Abstract
AIM: To observe the characteristics for the adaptive changes of bifidobacteria under the influence of 5-fluorouracil (5-FU).
METHODS:The growth and morphological characteristics of bifidobacteria in the presence of 5-FU were acquired by drug-sensitivity test, gram stain and atomic force microscopic scanning as well as the identification of the 5-FU-resitant isolates ......
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